Tetracyclines. VI. Some new aspects in the chemistry of oxazolones and their sulfur analogs

H Muxfeldt, J Behling, G Grethe…

文献索引：Muxfeldt,H. et al. Journal of the American Chemical Society, 1967 , vol. 89, p. 4991 - 4996

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被引用次数: 25

摘要

Abstract: Several 4-alkylidene-3-oxazalin-5-ones (“unsaturated azlactones”) and some sulfur analogs react with dimethyl 3-oxoglutarate in the presence of base to form derivatives of 6-aminocyclohexane-l, 3-dione. Some examples and applications of this reaction are described. he chemistry of oxazolones has riveted the attention T of organic chemists since the initial detection of a member of this class of compounds in 1883.'A very extensive ...