Tetrahedron Letters

Aziridines in one step from hydantoins via Red-Al mediated ring-contraction

F von Kieseritzky, J Lindström

文献索引：Von Kieseritzky, Fredrik; Lindstroem, Johan Tetrahedron Letters, 2011 , vol. 52, # 35 p. 4558 - 4561

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被引用次数: 3

摘要

However in our hands, attempted reductions with Red-Al often resulted in the appearance of a curious by-product in varying proportions. Typically, longer reaction times, elevated temperatures and the use of an excess of Red-Al seemed to favor the formation of this by-product, which we came to identify as aziridine 3. ... Intrigued by these findings, we proceeded to investigate the possibilities of steering the reaction so that it would consistently give aziridine as the ...