Phytochemistry

Carbazole alkaloids from Murraya koenigii

M Chakrabarty, AC Nath, S Khasnobis, M Chakrabarty…

文献索引：Chakrabarty, Manas; Nath, Amar C.; Khasnobis, Shampa; Chakrabarty, Manju; Konda, Yaeko; Harigaya, Yoshihiro; Komiyama, Kanki Phytochemistry, 1997 , vol. 46, # 4 p. 751 - 755

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被引用次数: 80

摘要

Two new alkaloids, 9-carbethoxy-3-methylcarbazole and 9-formyl-3-methylcarbazole, and a known metabolite, 3-methyl-carbazole were isolated from the roots of Murraya koenigii. All three compounds were identified by detailed spectral analyses including 2D NMR studies and their structures confirmed by synthesis. Of the two metabolites, the 9-formyl compound displayed weak cytotoxicity against both mouse melanoma B16 and adriamycin-resistant ...