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Synthesis, characterization and antiproliferative activity of transition metal complexes with 3-(4, 5-diphenyl-1, 3-oxazol-2-yl) propanoic acid (oxaprozin)

B Božić, J Rogan, D Poleti, N Trišović, B Božić…

文献索引:Bozic, Bojan D.J.; Rogan, Jelena R.; Poleti, Dejan D.; Trisovic, Nemanja P.; Bozic, Biljana D.J.; Uscumlic, Gordana S. Chemical and Pharmaceutical Bulletin, 2012 , vol. 60, # 7 p. 865 - 869

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被引用次数: 6

摘要

A series of novel Mn (II), Co (II), Ni (II), Cu (II) and Zn (II) complexes with oxaprozin (Hoxa), a non-steroidal anti-inflammatory drug, has been synthesized. The drug and complexes have been characterized by elemental and thermogravimetric (TG) analysis, Fourier transform (FT)-IR, 1 H-NMR, 13 C-NMR, UV-Vis spectroscopy and magnetic susceptibility measurements. The (pseudo) octahedral geometry has been proposed for all complexes ...