Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents

J Cai, M Sun, X Wu, J Chen, P Wang, X Zong…

文献索引：Cai, Jin; Sun, Min; Wu, Xiaoqing; Chen, Junqing; Wang, Peng; Zong, Xi; Ji, Min European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 702 - 712

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被引用次数: 25

摘要

Three series of novel 4-benzothiazole amino quinazolines Dasatinib derivatives have been designed and synthesized. The entire target compounds were investigated for their in vitro cytotoxic activity by the MTT-based assay against 6 human cancer cell lines. Compared ...