Bioorganic & medicinal chemistry

2-Benzyl-2-methylsuccinic acid as inhibitor for carboxypeptidase A. synthesis and evaluation

M Lee, Y Jin, DH Kim

文献索引：Lee, Mijoon; Jin, Yonghao; Kim, Dong H. Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1755 - 1760

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被引用次数: 20

摘要

Recently, Asante-Appiah et al.(Asante-Appiah, E.; Seetharaman, J.; Sicheri, F.; Yang, DS-C.; Chan, WW-C. Biochemistry1997, 36, 8710–8715) reported that 2-ethyl-2-methylsuccinic acid is a highly potent inhibitor for carboxypeptidase A (CPA), a prototypic zinc protease.