The Journal of Organic Chemistry

A total synthesis of phytol

K Sato, S Mizuno, M Hirayama

文献索引：Sato,K. et al. Journal of Organic Chemistry, 1967 , vol. 32, p. 177 - 180

全文：HTML全文

被引用次数: 59

摘要

A total synthesis of phytol from acetone is described. The synthesis has shorter stages than previously reported methods. Triethyl phosphonocrotonate anion could be condensed with carbonyl compounds to give the corresponding dienoic esters. The products were converted to &keto sulfoxides by reaction with methylsulfinyl carbanion and the sulfoxides were reduced with aluminum amalgam to give methyl ketones. Phytone, one of the compounds ...