Tetrahedron letters

First total synthesis of natural aplyolides B and D, ichthyotoxic macrolides isolated from the skin of the marine mollusk Aplysia depilans

A Spinella, T Caruso, C Coluccini

文献索引：Spinella, Aldo; Caruso, Tonino; Coluccini, Carmine Tetrahedron Letters, 2002 , vol. 43, # 9 p. 1681 - 1683

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被引用次数: 23

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A convergent pathway is described for the synthesis of the marine macrolides aplyolides B (2) and D (3). Stereoselective preparation of a key fragment was achieved by Sharpless asymmetric dihydroxylation of eneyne 10. ... The ichthyotoxic marine natural products aplyolides B (2) and D (3) were efficiently ...