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Australian Journal of Chemistry

Central nervous system active compounds. I. The synthesis of some caprolactam derivatives substituted at N1, C2 and C3

T Duong, RH Prager, AD Ward, DIB Kerr

文献索引:Duong; Prager; Ward; Kerr Australian Journal of Chemistry, 1976 , vol. 29, # 12 p. 2651 - 2665

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被引用次数: 10

摘要

Abstract The synthesis of a number of caprolactam derivatives with alkyl, aryl and hetero atom substituents at N1, C2 and C3 is described. Alkylation and arylation at C3 by a variety of methods is discussed. Some of these compounds are powerful convulsing agents; a few are depressants.