Molecules

A mild and facile one-pot synthesis of n-methyl-3-acyl-pyrroles

H Valizadeh, A Fakhari

文献索引：Valizadeh, Hassan; Fakhari, Ashraf Molecules, 2010 , vol. 15, # 5 p. 2972 - 2979

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被引用次数: 8

摘要

Abstract N-Methyl-3-acylpyrroles were synthesized via a multicomponent reaction of dimethylacetylene dicarboxylate (DMAD), N-methylhydroxylamine and acylchlorides in the presence of KHCO 3. For comparison both conventional and microwave protocols were examined in this procedure. The reaction is clean and gives the products in good to excellent yields under conventional heating conditions at 40 ºC in anhydrous ...