Claisen ortho ester rearrangement with trimethyl β-(methoxy) orthopropionate: a thermally stable synthon for the preparation of methyl α-substituted acrylates
S Raucher, JE Macdonald, RF Lawrence
文献索引：Raucher, Stanley; Macdonald, James E.; Lawrwence, Ross F. Tetrahedron Letters, 1980 , vol. 21, # 45 p. 4335 - 4338
Abstract Trimethyl β-(methoxy) orthopropionate, a compound which is thermally stable at 190 C for prolonged times, may be utilized as a synthon for the preparation of methyl α- substituted acrylates via Claisen ortho ester rearrangement with allylic alcohols followed by β-elimination of methanol with base.
