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3-Alkyl-6-methyl-5, 7-dioxo-4, 5, 6, 7-tetrahydro-1, 2, 3-triazolo [4, 5-d] pyrimidines and Their Alkylations

A Bozóová, A Rybár, J Alföldi…

文献索引:Bozoova, Alena; Rybar, Alfonz; Alfoeldi, Juraj; Basnakova, Gabriela Collection of Czechoslovak Chemical Communications, 1992 , vol. 57, # 6 p. 1314 - 1325

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被引用次数: 7

摘要

Abstract Alkylation of 3-alkyl-6-methyl-5, 7-dioxo-4, 5, 6, 7-tetrahydro-1, 2, 3-triazolo [4, 5-d] pyrimidines I with alkyl halides in dimethylformamide in the presence of potassium carbonate, or by analogous alkylation of sodium salts of compounds I afforded the respective 4-alkyl derivatives III but not 5-alkyloxy-3-alkyl-6-methyl-7-oxo-6, 7-dihydro-1, 2, 3- triazolo [4, 5-d] pyrimidines IV or isomeric 1, 3-dialkyl-6-methyl-5, 7-dioxo-4, 5, 6, 7- ...