Mild and efficient one-pot synthesis of 2-imidazolines from nitriles using sodium hydrosulfide as catalyst

M Sun, HT Wei, D Li, YG Zheng, J Cai…

文献索引：Sun, Min; Wei, Hong-Tao; Li, Dong; Zheng, You-Guang; Cai, Jin; Ji, Min Synthetic Communications, 2008 , vol. 38, # 18 p. 3151 - 3158

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被引用次数: 15

摘要

Imidazoline derivatives exhibit significant biological and pharmacological activities [ 1 1. (a) Greenhill , JV ; Lue , L. Progress in Medicinal Chemistry ; Elsevier : New York , 1993 ; Vol. 3 ; (b) Hardman, JG; Limbird, LE; Gilman, AG The Pharmacological Basis of Therapeutics, 10th ed.; Macmillan: New York, 2001; (c) Prisinzano, T.; Law, H.; Dukat, M.; Slassi, A.; MaClean, N.; Demchyshyn, L.; Glennon, RA Imidazoline-modified benzylimidazolines as h5-HT1D/1B ...