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3, 7-Dialkyl-8-alkyl-or-aryl-3, 7-dihydropurine-2, 6-diones

A Rybár, D Hesek, F Szemes, J Alföldi…

文献索引:Rybar, Alfonz; Hesek, Dusan; Szemes, Fridrich; Alfoeldi, Juraj; Tegza, Marian Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 9 p. 2257 - 2269

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被引用次数: 6

摘要

Abstract 3, 7-Dialkyl-8-alkyl-or-aryl-3, 7-dihydropurine-2, 6-diones XII-XIV were synthesized from 5-alkylamino-6-amino-1-alkyl-2, 4 (1H, 3H)-pyrimidinediones VII-IX by three methods: the first is based upon an acid catalyzed cyclization of the starting derivatives VII-IX with orthoesters of carboxylic acids in dimethylformamide. In the second and third methods the 5- ((N-acyl)(N-alkyl) amino) derivatives X, XI, obtained by acylation of VII-IX were cyclized ...