Tetrahedron Letters

Fluoroboric acid adsorbed on silica-gel (HBF 4–SiO 2) as a new, highly efficient and reusable heterogeneous catalyst for thia-Michael addition to α, β-unsaturated …

G Sharma, R Kumar, AK Chakraborti

文献索引：Sharma, Gaurav; Kumar, Raj; Chakraborti, Asit K. Tetrahedron Letters, 2008 , vol. 49, # 27 p. 4272 - 4275

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被引用次数: 71

摘要

Fluoroboric acid adsorbed on silica-gel (HBF4–SiO2) has been found to be a new and highly efficient heterogeneous catalyst for thia-Michael addition to α, β-unsaturated carbonyl compounds under solvent-free conditions. In the case of 1, 3-diaryl-2-propenones, the reactions are best carried out in MeOH. The rate of thia-Michael addition was dependent on the steric hindrance at the β-carbon of the α, β-unsaturated carbonyl substrate as well as ...