Journal of the Chemical Society (Resumed)

363. Cytotoxic compounds. Part IV. Substituted benzyl halides

R Grice, LN Owen

文献索引：Grice,R.; Owen,L.N. Journal of the Chemical Society, 1963 , p. 1947 - 1954

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被引用次数: 9

摘要

The three mercaptobenzyl alcohols were synthesised by reduction of methyl o-, m-, and P- mercaptobenzoate with lithium aluminium hydride, but reaction of each alcohol with thionyl chloride gave only resinous products; it therefore appears that the free mercaptobenzyl chlorides are as inaccessible as their phenolic analogues. 3-Mercaptobenzyl alcohol was also obtained by esterification, followed by reduction with lithium