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The ideal synthetic method aimed at the leads for an α2-blocker, an inhibitor of blood platelet aggregation, and an anti-osteoporosis agent

M Somei, T Iwaki, F Yamada, Y Tanaka…

文献索引:Somei, Masanori; Iwaki, Takako; Yamada, Fumio; Tanaka, Yoshio; Shigenobu, Koki; Koike, Katsuo; Suzuki, Nobuo; Hattori, Atsuhiko Heterocycles, 2006 , vol. 68, # 8 p. 1565 - 1569

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被引用次数: 18

摘要

抄録: According to the definition of the ideal synthetic method, an example aimed at the leads for an α2 blocker, an inhibitor of platelet aggregation, and an anti-osteoporosis agent is established starting from tryptamine. The originality rate, the intellectual property, and the application potential factors of the method are 71, 54, and 100, respectively. The method employs only conventional reagents and reaction conditions without using any protecting ...