Compelled by the interesting biological activities of 8-oxatropanes, many groups have embarked on the search for new methodologies to construct this bicyclic structure. For example, Molander and co-workers have reported a Lewis acid promoted double allylation of 1, 4-dicarbonyl compounds to construct 8-oxatropanes.[6] The same group later reported the syntheses of 8-oxatropanes using a TiCl4-promoted cycloaddition of a bis ( ...
