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Tetrahedron

A rapid and direct access to symmetrical/unsymmetrical 3, 4-diarylmaleimides and pyrrolin-2-ones

…, PS Hameed, S Padakanti, KR Yeleswarapu

文献索引:Pal, Manojit; Swamy, Nalivela Kumara; Hameed, P. Shahul; Padakanti, Srinivas; Yeleswarapu, Koteswar Rao Tetrahedron, 2004 , vol. 60, # 18 p. 3987 - 3997

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被引用次数: 35

摘要

1, 8-Diazabicyclo [5.4. 0] undec-7ene (DBU) facilitated the oxidative cyclization of phenacyl amide in the presence of atmospheric oxygen under environmentally friendly conditions. The reaction has been studied under various conditions and a plausible mechanism is proposed. This 'green'reaction proceeds via intramolecular ring closure of the amide followed by subsequent reaction with molecular oxygen where DBU played a crucial role. ...