前往化源商城

举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Drugs derived from cannabinoids. 1. Nitrogen analogs, benzopyranopyridines and benzopyranopyrroles

…, FE Granchelli, RK Razdan, JK Keller…

文献索引：Pars; Granchelli; Razdan; Keller; Teiger; Rosenberg; Harris Journal of Medicinal Chemistry, 1976 , vol. 19, # 4 p. 445 - 454

全文：HTML全文

被引用次数: 58

摘要

Various nitrogen analogs of A6aJOatetrahydrocannabinol were synthesized by a general procedure described in an earlier communication. Minimum effective doses (MEDds) and lethal doses (LDm's) were determined by a modified Irwin mouse screen after iv administration of compounds in PEG 200. The most potent compounds were the propargyl (5t), allyl (5m), and chloroallyl (50-q) derivatives. Overt behavioral effects (CNS ...

2-benzyl-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine结构式

2-benzyl-5,5-di...

~%

1,2,3,4-Tetrahydro-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-acetyloxy-2-(2-propenyl)-5H-[1]benzopyrano[4,3-c]pyridine结构式

1,2,3,4-Tetrahy...

查看详情

8-(1,2-Dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

8-(1,2-Dimethyl...

~%

1,2,3,4-Tetrahydro-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-acetyloxy-2-(2-propenyl)-5H-[1]benzopyrano[4,3-c]pyridine结构式

1,2,3,4-Tetrahy...

查看详情

2-allyl-8-(1,2-dimethyl-heptyl)-5,5-dimethyl-1,3,4,5-tetrahydro-2H-chromeno[4,3-c]pyridin-10-ol结构式

2-allyl-8-(1,2-...

~%

1,2,3,4-Tetrahydro-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-acetyloxy-2-(2-propenyl)-5H-[1]benzopyrano[4,3-c]pyridine结构式

1,2,3,4-Tetrahy...

查看详情

2-benzyl-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine结构式

2-benzyl-5,5-di...

~%

H-GFRLTNFGYFEPG-OH结构式

H-GFRLTNFGYFEPG-OH

查看详情

8-(1,2-Dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

8-(1,2-Dimethyl...

溴代丙炔结构式

~%

H-GFRLTNFGYFEPG-OH结构式

H-GFRLTNFGYFEPG-OH

查看详情

2-benzyl-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine结构式

2-benzyl-5,5-di...

~%

2-(Cyclobutylmethyl)-8-(1,2-dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

2-(Cyclobutylme...

查看详情

(溴甲基)环丁烷结构式

(溴甲基)环丁烷

8-(1,2-Dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

8-(1,2-Dimethyl...

~%

2-(Cyclobutylmethyl)-8-(1,2-dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

2-(Cyclobutylme...

查看详情

3-benzyl-8-(1,2-dimethyl-heptyl)-10-hydroxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one结构式

3-benzyl-8-(1,2...

~%

8-(1,2-Dimethylheptyl)-1,2,3,4-tetrahydro-10-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

8-(1,2-Dimethyl...

查看详情

1,3-Benzenediol,5-(1,2-dimethylheptyl)结构式

1,3-Benzenediol...

~%

8-(1,2-Dimethylheptyl)-1,2,3,4-tetrahydro-10-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

8-(1,2-Dimethyl...

查看详情

1-苄基-3-乙氧羰基-4-哌啶酮盐酸盐结构式

1-苄基-3-乙氧羰基-4-哌啶酮盐酸盐

~%

8-(1,2-Dimethylheptyl)-1,2,3,4-tetrahydro-10-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

8-(1,2-Dimethyl...

查看详情

8-(1,2-dimethyl-heptyl)-10-hydroxy-2-methyl-1,2,3,4-tetrahydro-chromeno[4,3-c]pyridin-5-one结构式

8-(1,2-dimethyl...

甲基碘化镁结构式

甲基碘化镁

~%

8-(1,2-Dimethylheptyl)-1,3,4,5-tetrahydro-2,5,5-trimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

8-(1,2-Dimethyl...

查看详情

2-benzyl-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine结构式

2-benzyl-5,5-di...

~%

8-(1,2-Dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2H-[1]benzopyrano[4,3-c]pyridin-10-ol结构式

8-(1,2-Dimethyl...

查看详情

3,5-二羟基甲苯结构式

3,5-二羟基甲苯

~%

1,2,3,4-Tetrahydro-10-hydroxy-8-methyl-3-(2-propynyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

1,2,3,4-Tetrahy...

查看详情

1-苄基-3-乙氧羰基-4-哌啶酮盐酸盐结构式

1-苄基-3-乙氧羰基-4-哌啶酮盐酸盐

~%

1,2,3,4-Tetrahydro-10-hydroxy-8-methyl-3-(2-propynyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

1,2,3,4-Tetrahy...

查看详情

1,2,3,4-Tetrahydro-3-benzyl-10-hydroxy-8-methyl-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

1,2,3,4-Tetrahy...

~%

1,2,3,4-Tetrahydro-10-hydroxy-8-methyl-3-(2-propynyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one结构式

1,2,3,4-Tetrahy...

查看详情