Electrophilic substitution of furo [3, 2??c] pyridine

JW Mcfarland, WA Essary, L Cilenti…

文献索引：McFarland,J.W. et al. Journal of Heterocyclic Chemistry, 1975 , vol. 12, p. 705 - 707

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被引用次数: 8

摘要

Abstract Furo [3, 2-c] pyridine (I) was nitrated to give 2-nitrofuro [3, 2-c] pyridine (II). Bromination and chlorination of I gave, respectively, 2, 3-dibromo-2, 3-dihydrofuro [3, 2-c] pyridine (III) and 2, 3-dichloro-2, 3-dihydrofuro [3, 2-c] pyridine (IV). Oxidation of I with hydrogen peroxide afforded furo [3, 2-c] pyridine 5-oxide (V) which was converted to I by phosphorus trichloride and to 4-chlorofuro [3, 2-c] pyridine (VI) by phosphorus oxychloride.