Introduction of pharmacophore groups into bis (indol-1-yl) maleimides and 6H-pyrrolo [3, 4: 2, 3][1, 4] diazepino [6, 7, 1-hi]-indolo-8, 10 (7H, 9H)-diones
Abstract The synthesis of bis (indol-1-yl) maleimides and polycondensed [1, 4] diazepines containing various functional groups, which are the analogs of biologically active indolo [2, 3- à] carbazoles, is described. Functional groups were introduced directly into [1, 4] diazepine and bis (indol-1-yl) maleimide molecules via electrophilic substitution reactions using precursors containing such functional groups.
