Csp 3-tellurium copper cross-coupling: synthesis of alkynyl tellurides a novel class of antidepressive-like compounds

AE Okoronkwo, B Godoi, RF Schumacher, JSS Neto…

文献索引：Okoronkwo, Afamefuna Elvis; Godoi, Benhur; Schumacher, Ricardo Frederico; Neto, Jose Sebastiao Santos; Luchese, Cristiane; Prigol, Marina; Nogueira, Cristina Wayne; Zeni, Gilson Tetrahedron Letters, 2009 , vol. 50, # 8 p. 909 - 915

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被引用次数: 11

摘要

We present here the results on the synthesis of functionalized alkynyl tellurides using the reaction of vinyl, alkynyl, and aryl tellurides with several alkynyl iodides catalyzed by copper iodide. The reaction proceeded cleanly under mild reaction conditions, at room temperature, in the absence of base and ligand giving alkynyl tellurides in acceptable yields. The obtained compounds 3a–c and 3m–o were screened for antidepressive-like activity using ...