Nitric oxide cheletropic traps (NOCTs) with improved thermal stability and water solubility

HG Korth, R Sustmann, P Lommes, T Paul…

文献索引：Korth; Sustmann; Lommes; Paul; Ernst; De Groot; Hughes; Ingold Journal of the American Chemical Society, 1994 , vol. 116, # 7 p. 2767 - 2777

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被引用次数: 86

摘要

Abstract: The search for nitric oxide cheletropic traps (NOCTs) of the 7, 7, 8, 8-tetraalkyl-o- quinodimethane type which would have properties appropriate for monitoring the formation of nitric oride in cell cultures and in vivo by magnetic resonance techniques is described. In addition to the necessary condition that a NOCT reacts rapidly with NO to yield a persistent nitroxide radical, two additional properties were sought:(i) thermal stability at the ...