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New heterocycles from 8??hydroxyquinoline via dipolar 1, 3??cycloadditions: Synthesis & biological evaluation

…, A Sebban, Z Dardari, M Boudouma…

文献索引:Bahloul, Abdelmejid; Sebban, Abdelfatah; Dardari, Zainaba; Boudouma, Mohammed; Kitane, Said; Belghiti, Touria; Joly, Jean-Pierre Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 2 p. 243 - 248

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被引用次数: 10

摘要

Abstract Diarylnitrilimine and arylnitriloxide dipoles react with two 8-hydroxyquinoline substrates to give respectively pyrazolinic and isoxazolinic derivatives. The structure of these new heterocycles was established on the basis of their spectroscopic data and by chemical methods. The inhibition activity of one of these heterocycles was evaluated in vitro against 8 pathogenic μ-organisms.