Polypeptides. Part XIII. Preparation of α-aza-amino-acid (carbazic acid) derivatives and intermediates for the preparation of α-aza-peptides

AS Dutta, JS Morley

文献索引：Dutta; Morley Journal of the Chemical Society. Perkin transactions 1, 1975 , # 17 p. 1712 - 1720

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被引用次数: 79

摘要

Esters and amides of several α-aza-amino-acids (carbazic acids), and intermediates of use in the introduction into peptides of α-aza-glycyl,-alanyl,-valyl,-leucyl,-isoleucyl,-phenylalanyl,- tyrosyl,-tryptophyl,-prolyl,-aspartyl,-asparaginyl,-glutamyl,-glutaminyl, and-pyroglutaminyl residues are described. t-Butyl 3-alkyl-or-aralkyl carbazates, obtained by catalytic hydrogenation of the corresponding hydrazones, were the most versatile intermediates; ...