Nickel-catalyzed conjugate addition of alkynyl groups to. alpha.,. beta.-unsaturated ketones

J Schwartz, DB Carr, RT Hansen…

文献索引：Schwartz, Jeffrey; Carr, Denise B.; Hansen, Robert T.; Dayrit, Fabian M. Journal of Organic Chemistry, 1980 , vol. 45, # 15 p. 3053 - 3061

全文：HTML全文

被引用次数: 82

摘要

workers' have improved upon this general reaction so that it would be useful in cases where the acetylenic moiety is a valuable intermediate. The use of Bl-alkylyl-g-borabicyclo [3.3. l] nonanes avoids the waste of the two residual alkynyl units on th. e reagent used in reaction 4. The following reaction in pentane at room temperature gives high yields of 4-alkynyl-2- butanones with methyl vinyl ketone and related ketones able to adopt a cisoid ...