Structural analogues of 5, 6-tetramethyleneuracil ribosides-Inhibitors of enzymes participating in nucleic acid synthesis

…, J Greger, K Fabianowska-Majewska

文献索引：Draminski; Frass; Greger; Fabianowska-Majewska Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 1 p. 280 - 285

全文：HTML全文

被引用次数: 1

摘要

The synthesis of new pyrimidine bases and their derivatives are of particular im- portaFlce in the search for antiviral and anticancer compounds. Some of synthetic nucleosides containing a substituent in position 5 of pyrimidine base are potential1 •2 or actually used antiviral drugs3 • It is assumed that the antiviral activity of the major- ity of these compounds is mainly due to their inhibiting effect on important enzymatic reactions4 • It has been observed that ...