Tetrahedron: Asymmetry

Tropos deoxycholic acid-derived biphenylphosphites: synthesis, stereochemical characterization and use as chiral ligands in the copper catalyzed conjugate addition …

S Facchetti, D Losi, A Iuliano

文献索引：Facchetti, Sarah; Losi, Debora; Iuliano, Anna Tetrahedron Asymmetry, 2006 , vol. 17, # 21 p. 2993 - 3003

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被引用次数: 20

摘要

Three new deoxycholic acid-based 5, 5′-substituted biphenylphosphites, 2–4, were synthesized and their stereochemical features were examined by CD and NMR spectroscopy, which allowed us to determine the sense of twist of the substituted biphenyl moiety as well as the extent of its prevalence in different solvents. Phosphites 1–4 were used as chiral ligands in the copper catalyzed conjugate addition of diethylzinc to acyclic ...