Tetrahedron

Iridium-catalyzed hydroboration of alkenes with pinacolborane

Y Yamamoto, R Fujikawa, T Umemoto, N Miyaura

文献索引：Yamamoto, Yasunori; Fujikawa, Rhyou; Umemoto, Tomokazu; Miyaura, Norio Tetrahedron, 2004 , vol. 60, # 47 p. 10695 - 10700

全文：HTML全文

被引用次数: 92

摘要

Hydroboration of terminal and internal alkenes with pinacolborane (1.2 equiv) was carried out at room temperature in the presence of an iridium (I) catalyst (3mol%). Addition of dppm (2equiv) to [Ir (cod) Cl] 2 gave the best catalyst for hydroboration of aliphatic terminal and internal alkenes at room temperature, resulting in addition of the boron atom to the terminal carbon of 1-alkenes with more than 99% selectivities. On the other hand, a complex ...