Tetrahedron

Synthesis of cyclic hydroxamic acids from aliphatic nitro compounds

A Thomas, S Rajappa

文献索引：Thomas, Achamma; Rajappa, Srinivasachari Tetrahedron, 1995 , vol. 51, # 38 p. 10571 - 10580

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被引用次数: 17

摘要

A novel method far the synthesis of five membered α-substituted cyclic hydroxamic acids from aliphatic nitro compounds including nitro acetic acid derivatives is described. Michael addition of allyl acrylate to these compounds followed by Pd (0) catalyzed intra molecular allyl transfer and subsequent reduction of the tertiary nitro group results in a new class of compounds related to Nhydroxy pyroglutamic acid.