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Tetrahedron Letters

Concise, regiocontrolled synthesis of yangjinhualine A

J Boukouvalas, LC McCann

文献索引:Boukouvalas, John; McCann, Lucas C. Tetrahedron Letters, 2011 , vol. 52, # 11 p. 1202 - 1204

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被引用次数: 15

摘要

The first synthesis of yangjinhualine A, a recently isolated α, β-disubstituted γ- hydroxybutenolide from the Chinese medicinal herb Datura metel L., has been accomplished in concise, entirely regiocontrolled fashion through the combined use of Suzuki–Miyaura cross-coupling and 2-silyloxyfuran oxyfunctionalization.