Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases

…, G Surpateanu, Q Wang, P Retailleau…

文献索引：Shinomiya, Kazuki; Hano, Yoshio; Nomura, Taro Heterocycles, 2000 , vol. 53, # 4 p. 877 - 886

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被引用次数: 19

摘要

... Volume: Page: ... 3 (GSK3),(2) dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A),(3) and cdc2-like kinase CLK1(4) are serine ... diseases.(1) Today, around 250 small molecule kinase inhibitors are undergoing clinical trials for the treatment of ...