The advent of Barbier 1 and Grignard reactions heralded a new era in organic chemistry. Although generally ignored for a long time, there has been considerable interest in the Barbier reaction vis a vis other organometallic reactions for the formation of carbon–carbon bonds. Recently, indium mediated Barbier reaction of a variety of functional groups such as aldehydes, ketones, anhydrides, acid chlorides, imides, activated alkenes, alkynes, cyclopropenes, ...
