Indium-catalyzed direct chlorination of alcohols using chlorodimethylsilane-benzil as a selective and mild system

M Yasuda, S Yamasaki, Y Onishi…

文献索引：Onishi, Yoshiyuki; Ogawa, Daigo; Yasuda, Makoto; Baba, Akio Journal of the American Chemical Society, 2002 , vol. 124, # 46 p. 13690 - 13691

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被引用次数: 67

摘要

The InCl3-catalyzed reaction of alcohols with chlorodimethylsilane (HSiMe2Cl) in the presence of benzil gave the corresponding organic chlorides under mild conditions. Benzil significantly changes the reaction course because the reducing product through dehydroxyhydration was obtained in the absence of benzil. The secondary or tertiary alcohols were effectively chlorinated. The substrates bearing acid-sensitive functional ...