Synthesis of 4??amino??3??(β??D??ribofuranosyl) pyrazole??5??carboxarnidc via ring fission of formycin derivatives and purification using high pressure liquid …

AF Lewis, RA Long, LWR Roti…

文献索引：Lewis,A.F. et al. Journal of Heterocyclic Chemistry, 1976 , vol. 13, p. 1359 - 1361

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被引用次数: 9

摘要

Abstract Two methods have been established for the synthesis of 4-amino-3-(β-D- ribofuranosyl)-pyrazole-5-carboxamide. This nucleoside ean be viewed as a potentially versatile intermediate for the synthesis of various bieyelic C-nueleosides. The use of HPLC for the final purification of “pure” samples on the basis of elemental analysis is described.