Synthesis and Biological Properties of Aminoalkylhydrazines. A Unique Nitrogen-Nitrogen Scission of 1-(2-Diethylaminoethyl)-2-(1-phenyl-2-propyl) hydrazine

EF Elslager, EA Weinstein…

文献索引：Elslager,E.F. et al. J. Med. Chem., 1964 , vol. 7, p. 493 - 500

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被引用次数: 17

摘要

Several 2-(3-aminopropyl)-l, l-dialkylhydrazines (IIIa-d, Table I) were prepared by reduction of the appropriate 3-(2, 2-dialkylhydrazino) propionitriles (IIa-d) with lithium aluminum hydride. Treatment of various dialkylaminoalkyl chlorides with excess hydrazine gave the corresponding (dialkylaminoalky1) hydrazines IIV, Table 11) as the preponderant products; small amounts of the 1, l-bis (dialkylaminoalky1) hydrazines (V, Table 111) were isolated ...