Tetrahedron letters

Functionalized ketones by iron mediated reaction of grignard reagents with acyl chlorides

C Cardellicchio, V Fiandanese, G Marchese…

文献索引：Cardellicchio, C.; Fiandanese, V.; Marchese, G.; Ronzini, L. Tetrahedron Letters, 1987 , vol. 28, # 18 p. 2053 - 2056

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被引用次数: 76

摘要

Abstract The iron (III)-catalyzed cross-coupling reaction between Grignard reagents and acyl chlorides was found to be widely applicable to the synthesis of various functionalized ketones in good yields under mild conditions; the series of examples includes the synthesis of chiral methyl ketones and symmetric diketones.