Aromatization of enamines promoted by a stoichiometric amount of palladium (II) salts: A novel method for the synthesis of aromatic amines

T Ishikawa, E Uedo, R Tani, S Saito

文献索引：Ishikawa; Uedo; Tani; Saito Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 186 - 191

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被引用次数: 30

摘要

Enamines (1a-r) prepared from cyclohexanones, cyclohexane-1, 3-diones, or tetralones led to arylamines (2a-r) in one pot when treated with a stoichiometric amount of palladium salts [PdCl2 (MeCN) 2] in acetonitrile in the presence of triethylamine at room temperature or at elevated temperature, in some cases for 5 min to 2 h. The initial electrophilic attack of palladium chloride on the β-carbon of the enamines led to a σ-palladium species (8) ...