Adrenergic Blocking Agents. II. N-Aralkyl-β-haloethylamines1

JF Kerwin, TF Herdegen, RY Heisler…

文献索引：Kerwin et al. Journal of the American Chemical Society, 1950 , vol. 72, p. 940,3983,3985

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被引用次数: 4

摘要

All of the 6-chloroethylamine hydrochlorides (see Table I) were formed from the corresponding N, N-disubstituted ethanolamines and thionyl chloride. The two hydroxy substituted 0-bromoethylamine hydrobromides in Table I were prepared by heating N-( pmethoxyphenylisopropy1)-N benzylethanolamine (or the 3, 4-dimethoxy compound) with concentrated hydrobromic acid to effect simultaneous demethylation and replacement of ...