Tetrahedron

Copper-catalyzed oxidative cyclization of chalcone and benzylic amine leading to 2, 5-diaryl oxazoles via carbon–carbon double bond cleavage

D Liu, J Yu, J Cheng

文献索引：Liu, Dongfang; Yu, Jintao; Cheng, Jiang Tetrahedron, 2014 , vol. 70, # 6 p. 1149 - 1153

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被引用次数: 1

摘要

Abstract A copper-catalyzed oxidative cyclization of chalcone with benzylic amine is achieved, providing 2, 5-diaryl oxazoles in moderate to good yields. The procedure employs O 2 as a clean oxidant and involves an oxidative cleavage of the C double bond; length as m-dash