The function of the carbonyl moiety at C-3 of steroid hormones in eliciting biological responses has been the subject of some study in this1 and other lab~ ratories.~~~ In the course of our search for claudogenic steroids, we needed to prepare estr-4-ene-3a, l7/3-diol by reduction of 19-nortestosterone with LiAlH4. Purification of the crude product gave estr-4- ene-3/3, 17P-diol and estra-3, 5-dien-
![(8R,9S,10R,13S,14S,17S)-3,10,13-trimethyl-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-ol结构式](https://image.chemsrc.com/caspic/420/60397-35-5.png)
