Hypocholesteremic Agents. III. 1 Basic Carbinols and Related Compounds

JH Short, U Biermacher, DA Dunnigan…

文献索引：Short,J.H. et al. J. Med. Chem., 1965 , vol. 8, p. 223 - 230

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被引用次数: 4

摘要

A series of 58 basic carbinols and related compounds has been synthesized, mostly by means of the Grignard reaction, and examined for hypocholesteremic activity. One compound, a-[P (2-diethylaminoethoxy) phenyl]-cu-phenyl-5-acenaphthenemethano1, proved to be considerably more potent than triparanol in both rats and mice.