Chemistry letters

Green protocol for the synthesis of vicinal-halohydrins from oxiranes using the [Bmim] PF6/LiX reagent system

JS Yadav, BVS Reddy, CS Reddy, K Rajasekhar

文献索引：Yadav; Reddy; Reddy, Ch. Srinivas; Rajasekhar Chemistry Letters, 2004 , vol. 33, # 4 p. 476 - 477

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被引用次数: 15

摘要

Epoxides undergo rapid ring-opening with lithium halides in [bmim] PF 6 or [bmim] BF 4 ionic liquids under mild and neutral conditions to afford the corresponding vic-halohydrins in high to quantitative yields. The epoxides show enhanced reactivity in ionic liquids thereby reducing reaction times and improving the yields significantly. The recovered ionic liquid can be reused in three to four subsequent runs with consistent activity.