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Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds

A Dantas de Araujo, C Christensen…

文献索引:Dantas De Araujo, Aline; Christensen, Caspar; Buchardt, Jens; Kent, Stephen B. H.; Alewood, Paul F. Chemistry - A European Journal, 2011 , vol. 17, # 50 p. 13983 - 13986

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被引用次数: 1

摘要

Design and synthesis of novel and structurally diverse heterocyclic compounds as peptidomimetics is an area of intensive research in the field of peptide, combinatorial and medicinal chemistry.[1] One common strategy in peptide mimetic design is to restrict the conformational freedom available to the peptide by replacement of the native peptidyl structure by rigid mimetic scaffolds. In many instances, stabilisation of a biologically active ...