Synlett

Expeditious Syntheses of (±)-allo-Sedamine and (±)-allo-Lobeline via a Combination of Aza-Sakurai-Hosomi and Hydroformylation Reactions

T Spangenberg, E Airiau, M Donnard, M Billet, A Mann

文献索引：Spangenberg, Thomas; Airiau, Etienne; Thuong, Mathieu Bui The; Donnard, Morgan; Billet, Manuella; Mann, Andre Synlett, 2008 , # 18 p. 2859 - 2863

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被引用次数: 13

摘要

A large body of work has been devoted to the preparation of homoallylamines, [¹] the main substrates for the construction of piperidines which are privileged scaffolds for biomolecules. Indeed, homoallylamines have a great chemical potential due to the presence of a terminal double bond enabling a number of chemical manipulations, such as metathesis, oxidative hydroboration or hydroformylation. Several syntheses of naturally occurring piperidines are performed with functionalized ...