Tetrahedron letters

Chiral dithiolane sulphoxides: An efficient stereoselective synthesis of (R) and (S)-3-benzoyloxy-2-butanone

MT Barros, AJ Leitão, CD Maycock

文献索引：Barros; Barros, M. Teresa; Leitao; Leitao, Alcino J.; Maycock; Maycock, Christopher D. Tetrahedron Letters, 1995 , vol. 36, # 36 p. 6537 - 6540

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被引用次数: 12

摘要

The effect of the addition of water on the asymmetric oxidation of an acyl dithiane and an acyl dithiolane has been studied. The use of enantiomerically pure dithiolane sulphoxides is demonstrated in a highly selective synthesis of (R)-3-benzoyloxy-2-butanone which depends upon a diastereoselective ketone reduction.