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Journal of heterocyclic chemistry

The synthesis of a series of (α??amino) indol??3??yl ketones

JP Sanchez, RF Parcell

文献索引:Sanchez, Joseph P.; Parcell, Robert F. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 469 - 474

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被引用次数: 4

摘要

Abstract A series of [(α-amino) indol-3-yl]-2-methyl-1-propanones and [(α-amino) indol-3-yl] cyclopentylmethanones has been synthesized by a variety of reductive reactions performed on the corresponding series of (α-azido)-indol-3-yl ketones. One of the more interesting reductive procedures involved the palladium-catalyzed decomposition of formic acid with the formation of hydrogen in situ. The (α-azido) ketones were prepared in excellent yield by ...