Synthesis and biological evaluation of a series of (benzo [d] thiazol-2-yl) cyclohexanecarboxamides and (benzo [d] thiazol-2-yl) cyclohexanecarbothioamides

NH Nam, P Dung, P Thi, PT Thuong…

文献索引：Nam, Nguyen Hai; Dung, Phan Thi Phuong; Thuong, Phuong Thien; Hien, Tran Thi Medicinal Chemistry, 2010 , vol. 6, # 3 p. 159 - 164

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被引用次数: 2

摘要

A series of benzothiazole derivatives including N-(benzo [d] thiazol-2-yl) cyclohexanecarboxamides (2a-g) and N-(benzo [d] thiazol-2-yl) cyclohexancarbothioamides (3b-d) have been synthesized and evaluated for cytotoxic and antimicrobial activities. Two compounds including N-(6-ethoxybenzo [d] thiazol-2-yl) cyclohexanecarboxamide (2c) and N-(6-ethoxybenzo [d] thiazol-2-yl) cyclohexanecarbothiamide (3c) demonstrated ...