The Journal of organic chemistry

Lewis base-promoted hydrosilylation of cyclic malonates: Synthesis of β-substituted aldehydes and γ-substituted amines

CG Frost, BC Hartley

文献索引：Frost, Christopher G.; Hartley, Benjamin C. Organic Letters, 2007 , vol. 9, # 21 p. 4259 - 4261

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被引用次数: 18

摘要

The Lewis base-promoted hydrosilylation of cyclic malonates provides a convenient synthesis of β-substituted aldehydes. No over-reduction to the primary alcohol is observed as the aldehyde functionality is protected until a subsequent hydrolysis step. The utility of the